Broad Spectrum

Effective on Biofilm

1. EFFICACY:  DoxyKlor vs. chlorine, quaternary ammonium & alcohol products
Compared to the active ingredient in DoxyKlor, alcohols and quaternary ammonium containing products are less (or not) effective against viruses and mycobacteria. Moreover, alcohols & 'quats' have no credible efficacy against bacterial spores in acceptable contact times & must be rinsed from surfaces (thus potentially adding bacteria to or introducing moisture to accelerate bacterial growth on the surface.)

Like chlorine, chlorine dioxide disinfects through oxidation in as little as 15 seconds. However, chlorine dioxide is the only biocide that is a molecular free radical. (It has 19 electrons and has a preference for substances that give off or take up an electron.) Chlorine dioxide only reacts with substances that give off an electron. Chlorine dose the opposite - it adds a chlorine atom to or substitutes a chlorine atom from the substance it reacts with. This difference makes chlorine dioxide a far more selective oxidizer than chlorine. In the real world, this difference means the residual concentration of chlorine dioxide is much higher than the residual concentration of chlorine in instances of heavy pollution.

Contrary to chlorine, chlorine dioxide is effective at a pH of between 5 and 10. The efficiency increases at high pH values, while the active forms of chlorine are greatly influenced by pH. Under normal circumstances, chlorine dioxide does not hydrolyze. This is why the oxidation potential is high and the disinfection capacity is not influenced by pH. Both temperature and alkalinity of the water do not influence the efficiency. At the concentrations required for disinfection, chlorine dioxide is not corrosive. Chlorine dioxide is more water-soluble than chlorine.

Active chlorine dioxide is the ”go-to” agent Anthrax spore decontamination of Federal buildings for some time, demonstrating active chlorine dioxide's public record as a superior high-level sporicidal disinfectant. Chlorine, "quats" and alcohol are not. 

2. SAFETY: DoxyKlor vs. hydrogen peroxide products

Hydrogen peroxide is a liquid at room temperature and therefore condenses on surfaces. In a spill/leak emergency or industrial high-concentration or high-volume usage situation, this condensate takes a long time to dry & evaporate, taking hours, or even a day, before it is safe to return to the affected space.

The active chlorine dioxide in DoxyKlor remains a gas within a liquid (its “delivery system”). High efficacy at low dosage rates means DoxyKlor is rarely used at high concentrations.  Moreover, even in a high volume usage or spill/leak emergency, large quantities can be aerated to quickly evaporate the gas from full concentration to safe levels. This means that in the event of leakage, chlorine dioxide gas can be removed making the area safe in 30 minutes or less.

3. KILL MECHANISM: DoxyKlor vs. other antimicrobials

Chlorine dioxide is unique. It directly reacts with microorganism cell walls; it is not dependent on reaction time or concentration. Chlorine dioxide kills microorganisms even when they are inactive, which one of the reasons microorganisms don't build resistance to chlorine dioxide.

The mechanism by which DoxyKlor eliminates bacteria is this: the cell wall is penetrated by chlorine dioxide, interrupts cellular process & reacts with amino acids & RNA. In eliminating viruses, chlorine dioxide reacts with peptone & prevents of protein formation. These mechanisms are why chlorine dioxide is more effective against viruses than other antimicrobials, including ozone. Since chlorine dioxide’s primary mode of microbial kill is via electron exchange within molecular structures, harmful microbial organisms can't develop resistance. This different kill mechanism mitigates rapidly developing resistance (e.g. MRSA). Unlike with bleach, idophor, phenol, alcohol or hydrogen peroxide based products, users do not have to increase the amount or concentration of product used to achieve consistently acceptable pathogen elimination on target surfaces. 


The problem with many oxidizers is that of excess reactivity. When a very reactive oxidizing disinfectant encounters a pathogen, all the oxidation power is expended instantly on the first encounter, with nothing left in reserve. Lower reactivity and a better delivery system is the greatest strength & part of the reason DoxyKlor excels in biofilm penetration where other antimicrobial active ingredients, do not.  In addition, the suspended chlorine dioxide in DoxyKlor remains gaseous in solution, the tiny but mighty chlorine dioxide molecule has the ability to penetrate the slime layers of bacteria to oxidize polysaccharide matrices that keep biofilm together.

4. CORROSION: DoxyKlor vs. 'stabilized chlorine dioxide' & peracetic acid products

Peracetic acid (also known as peroxyacetic acid, or PAA ) is extremely corrosive to skin, metals, plastics, pretty much everything, requiring the addition of fillers or buffers to enable its practical use as a disinfectant product. This essentially lowers the oxidation (corrosion) potential a bit, but in the process creates a weaker, less robust oxidant and disinfectant.


DoxyKlor's low oxidation capacity (corrosion factor) makes it a clear winner for practical, real-world use, such as sanitizing delicate reverse-osmosis membranes. So-called 'stabilized chlorine dioxide' is formulated using a different process, making it less pure, less stable & prone to impurities. In addition, 'stabilized chlorine dioxide' solutions produce acidic byproducts that cause corrosion. Active chlorine dioxide products utilize a pure chlorine dioxide, which is both scientifically& statistically less corrosive than hydrogen peroxide (which condenses on surfaces, increasing corrosivity & contributing to incompatibility with epoxy finishes on walls, flooring & other materials.


Comprised of active chlorine dioxide (in a shelf-stable, not 'stabilized' solution), DoxyKlor is compatible with the majority of materials commonly found in residential, commercial & industrial environments.

5. RESIDUE: DoxyKlor vs. 'stabilized chlorine dioxide' products
Not all chlorine dioxide is alike; neither are all chlorine dioxide products. Most 'stabilized chlorine dioxide' products leave residue from acidic byproducts that requires post-treatment rinsing. Their residues are directly attributed to their specific formulations & composition.


Pure, active chlorine dioxide gas has been proven NOT to leave a residue. In fact, one of the first commercial uses of active chlorine dioxide gas was for the sterilization of implantable contact lenses. FDA approval of the process required ample proof of the claim that active chlorine dioxide gas did not leave a residue. DoxyKlor is formulated using nothing but pure ingredients (including active chlorine dioxide) proven not to leave residue. 

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